Matthew P. DeLisa

William L. Lewis Professor of Engineering
Smith School of Chemical and Biomolecular Engineering, College of Engineering

Contact Information

254 Olin Hall
Cornell University
Ithaca, NY 14853
p: (607) 254-8560

Matthew P. DeLisa

William L. Lewis Professor of Engineering
Smith School of Chemical and Biomolecular Engineering, College of Engineering

Expertise
Biomolecular engineering; biopharmaceuticals; cellular machinery; glycobiology; protein engineering; synthetic biology

Current Research Interest
Understanding and controlling the molecular mechanisms underlying protein biogenesis—folding and assembly, membrane translocation, and post-translational modifications—in the complex environment of a living cell

Distinction
Cornell College of Engineering Research Excellence Award
American Institute for Medical and Biological Engineering, Fellow
Office of Naval Research, Young Investigator Program
Arnold and Mabel Beckman Foundation, Beckman Young Investigator Award
National Science Foundation CAREER Award

Selected Publications
Chen, Linxiao, Jenny L. Valentine, Chung-Jr Huang, Christine E. Endicott, Tyler D. Moeller, Jed A. Rasmussen, Joshua R. Fletcher, Joseph M. Boll, Joseph A. Rosenthal, Justyna Dobruchowska, Zhirui Wang, Christian Heiss, Parastoo Azadi, David Putnam, M. Stephen Trent, Bradley D. Jones, and Matthew P. DeLisa. “Outer Membrane Vesicles Displaying Engineered Glycotopes Elicit Protective Antibodies.Proceedings of the National Academy of Sciences USA 113, no. 26 (2016): E3609-E3618.

Ollis, Anne A., Sheng Zhang, Adam C. Fisher, and Matthew P. DeLisa. “Engineered Oligosaccharyltransferases with Greatly Relaxed Acceptor Site Specificity.Nature Chemical Biolology 10 (2014): 816–822.

Cornell Research Website Article
Glycoengineering Designer Therapeutics