Matthew P. DeLisa

William L. Lewis Professor of Engineering
William L. Lewis Professor of Engineering, College of Engineering

Contact Information

254 Olin Hall
Cornell University
Ithaca, NY 14853
p: (607) 254-8560

Matthew P. DeLisa

William L. Lewis Professor of Engineering
William L. Lewis Professor of Engineering, College of Engineering

Expertise

Biomolecular engineering; biopharmaceuticals; cellular machinery; glycobiology; immunoengineering; protein engineering; synthetic biology

Current Research Interest

Understanding and controlling the molecular mechanisms underlying protein biogenesis—folding and assembly, membrane translocation, and post-translational modifications—for the discovery and development of therapeutic proteins and vaccines

Distinction

American Academy of Microbiology Fellow
American Institute for Medical and Biological Engineering Fellow
MIT Technology Review 35 Top Young Innovators Under 35
Office of Naval Research Young Investigator Program
Arnold and Mabel Beckman Foundation Beckman Young Investigator Award
National Science Foundation CAREER Award

Selected Publications

Jaroentomeechai, Thapakorn, Jessica C. Stark, Aravind Natarajan, Cameron J. Glasscock, Laura E. Yates, Karen J. Hsu, Milan Mrksich, Michael C. Jewett, and Matthew P. DeLisa. “Single-Pot Glycoprotein Biosynthesis Using a Cell-Free Transcription-Translation System Enriched with Glycosylation Machinery.” Nature Communications 9 (2018): 2686.

Chen, Linxiao, Jenny L. Valentine, Chung-Jr Huang, Christine E. Endicott, Tyler D. Moeller, Jed A. Rasmussen, Joshua R. Fletcher, et al. “Outer Membrane Vesicles Displaying Engineered Glycotopes Elicit Protective Antibodies.” Proceedings of the National Academy of Sciences USA 113, no. 26 (2016): E3609-E3618.

Cornell Research Website Article

Glycoengineering Designer Therapeutics