Dave Burbank
Margaret S. Bynoe
Professor
Microbiology and Immunology, College of Veterinary Medicine
Contact Information
C5 165 Veterinary Medical College
Cornell University
Ithaca, NY 14853
p:
(607) 253-4023
Margaret S. Bynoe
Professor
Microbiology and Immunology, College of Veterinary Medicine
Expertise
Blood brain barrier, structure and function; inflammatory bowel diseases; mechanisms of immune cells’ breach of central nervous system barriers; mechanisms of adenosine/adenosine receptor axis regulation of inflammation; mechanism of the gut-brain axis
Current Research Interest
Mechanisms of neurotropic pathogens’ influence on the brain and neurodegenerative diseases; trafficking of multi-drug resistant transporters; multi-modal regulation of A2A adenosine receptor, protein structure/function; role of A1 and A2A adenosine receptors in multiple sclerosis
Distinction
Pfizer Animal Health Award for Research Excellence
Albert Einstein College of Medicine, Graduate Programs in Biomedical Sciences, Fourth Annual PREP Regional Symposium Keynote Speaker
American Association for Immunologists Lustgarten-eBioscience Memorial Award
Cornell University Schwartz Alumni Research Fund Award
Selected Publications
Torres, Luisa, Sudie-Ann Robinson, Do-Geun Kim, Angela Yan, Thomas A. Cleland, and Margaret S. Bynoe. “Toxoplasma Gondii Alters NMDAR Signaling and Induces Signs of Alzheimer’s Disease in Wild-Type, C57BL/6 Mice.” Journal of Neuroinflammation 15, no. 1 (2018): 57.
Kim, Do-Geun and Margaret S. Bynoe. “A2A Adenosine Receptor Modulates Drug Efflux Transporter P-glycoprotein at the Blood-Brain Barrier.” The Journal of Clinical Investigation 126, no. 5 (2016): 1717-1733.