Li Gan

Director, Helen and Robert Appel Alzheimer’s Disease Research Institute; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine
Burton P. and Judith B. Resnick Distinguished Professor in Neurodegenerative Diseases

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Provided

Contact Information

Weill Cornell Medicine Helen and Robert Appel Alzheimer’s Disease Research Institute
413 E. 69th Street
New York, NY 10021

Li Gan

Director, Helen and Robert Appel Alzheimer’s Disease Research Institute; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine
Burton P. and Judith B. Resnick Distinguished Professor in Neurodegenerative Diseases

Expertise

Neurodegeneration; neuroinflammation; proteostasis; microglia; lysosome

Current Research Interest

Dissecting the mechanisms underlying the brain’s resilience against neurodegeneration and harnessing our innate resilience program for therapeutic strategies

Distinction

Helis Foundation Award for Parkinson’s Disease and Neurodegenerative Research
Co-Chair, Tau 2022 Global Conference
Associate Editor, Science Advances
Program Committee Member, Society for Neuroscience
Inge Grundke-Iqbal Award for Alzheimer’s Research
Glenn Award for Biological Mechanisms of Aging

Selected Publications

Wang, Chao, Li Fan, Rabia R. Khawaja, Bangyan Liu, Lihong Zhan, Lay Kodama, Marcus Chin, et al. “Microglial NF-κB Drives Tau Spreading and Toxicity in a Mouse Model of Tauopathy.” Nature Communications 13, no. 1 (April 12, 2022): Article No. 1969.

Tracy, Tara E., Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, et al. “Tau Interactome Maps Synaptic and Mitochondrial Processes Associated with Neurodegeneration.” Cell 185, no. 4. (February 17, 2022): 712–728.

Cornel Research Website Article

Catching the Memory Thief