Lewis C. Cantley

Professor of Cancer Biology in Medicine
Medicine/Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine

Contact Information

413 East 69th Street, Room 1362, Box 50
Weill Cornell Medicine
New York, NY 10021
p: (646) 962-6132
f:
(646) 962-0575

Lewis C. Cantley

Professor of Cancer Biology in Medicine
Medicine/Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine

Expertise

Cell metabolism; cell signaling; cancer biology; biochemistry; molecular biology; physiology

Current Research Interest

Further elucidating the role of PI-3-kinase in anabolic signaling by insulin, IGF-1, and other growth factors; metabolic regulation and oncogenic transformation; NRF2 and the serine pathway; Vitamin C as a potential treatment for RAS-mutant tumors; identifying biomarkers and novel therapeutic targets; drug development and delivery 

Distinction

Wolf Prize in Medicine
Canada Gairdner International Award
Breakthrough Prize in Life Sciences
American Academy of Arts and Sciences
National Academy of Sciences
National Academy of Medicine

Selected Publications

Paddock, Marcia N., Seth J. Field, and Lewis C. Cantley. “Treating Cancer with Phosphatidylinositol-3-kinase Inhibitors: Increasing Efficacy and Overcoming Resistance.” Journal of Lipid Research 60 (2019): 747-752.

Ferguson, Fleur M., Zainab M. Doctor, Scott B. Ficarro, Christopher M. Browne, Jarrod A. Marto, Jared L. Johnson, Tomer M. Yaron, et al. “Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity.” Cell Chemical Biology 26, no. 6 (2019): 804-817.

Cornell Research Website Video

Solving Cancer through Collaboration