Structural biology; protein structure-function; biophysics; biochemistry; cell biology
Current Research Interest
Molecular mechanisms controlling bacterial biofilm formation, associated with bacterial adaptation and chronic infections; membrane fusion and fission in eukaryotes, fundamental cellular processes affected in several neurological disorders
PEW Scholar in the Biomedical Sciences
Robert N. Noyce Assistant Professor in Life Science and Technology
Pfizer Animal Heath Award for Research Excellence
Chatterjee, Debashree, Richard B. Cooley, Chelsea D. Boyd, Ryan A. Mehl, George A. O'Toole, and Holger Sondermann. “Mechanistic Insight into the Conserved Allosteric Regulation of Periplasmic Proteolysis by the Signaling Molecule Cyclic-di-GMP.” eLife 3:e03650 (2014).
Byrnes, Laura J., Avtar Singh, Kylan Szeto, Nicole M. Benvin, John P. O'Donnell, Warren R. Zipfel, and Holger Sondermann. “Structural Basis for Conformational Switching and GTP Loading of the Large G Protein Atlastin.” EMBO Journal 32, no. 3 (2013): 369-84.