Jesse Winter
Frederick R. Maxfield
Professor
Biochemistry, Weill Cornell Medicine
Contact Information
1300 York Avenue, Room E-215
Weill Cornell Medicine
New York, NY 10065
p:
(212) 746-6405
f:
(212) 746-8875
Frederick R. Maxfield
Professor
Biochemistry, Weill Cornell Medicine
Expertise
Optical microscopy and biophysical techniques; digital imaging devices; confocal microscopes; multiphoton microscopy; automated microscopy systems; and image processing computers for analyzing processes that occur at specific sites within cells
Research Interest
Lipid and protein trafficking in cells, atherosclerosis, macrophages, microglial biologogy, degradation of Alzheimer's amyloid
Selected Publications
Solé-Domènech, Santiago, Ana V. Rojas, Gia G. Maisuradze, Harold A. Scheraga, Peter Lobel, and Frederick R. Maxfield. “Lysosomal Enzyme Tripeptidyl Peptidase 1 Sestabilizes Fibrillar Amyloid-Beta by Multiple Endoproteolytic Cleavages within the ß-Sheet Domain.” Proceedings of the National Academy of Sciences USA 115, no. 7 (2018): 1493-1498.
Singh, Rajesh K., Valéria C. Barbosa-Lorenzi, Frederik W. Lund, Inna Grosheva, Frederick R. Maxfield, and Abigail S. Haka. (2016) “Degradation of Aggregated LDL Occurs in Complex Extracellular Sub-Compartments of the Lysosomal Synapse.” Journal of Cell Science 129 (2016): 1072-1082.