David G. Russell
Microbial pathogenesis; Mycobacterium tuberculosis (Mtb); HIV; innate immunity; macrophage biology; antimicrobial agents
Current Research Interest
Host-pathogen interplay with an emphasis on macrophages and the infectious agents Mycobacterium tuberculosis (Mtb) and HIV; the determinants of disease progression versus control in tuberculosis; how the host’s immune environment impacts the susceptibility of Mtb to frontline drugs; the identification of new anti-tuberculosis drugs that exploit the host’s immune environment
Burroughs Wellcome Scholar Award in Parasitology
Fellow of the American Association for the Advancement of Science
Honorary Professor of Immunology, College of Medicine, Malawi
Liu, Yancheng, Shumin Tan, Lu Huang, Robert B. Abramovitch, Kyle H. Rohde, Matthew D. Zimmerman, Chao Chen, Véronique Dartois, Brian C. VanderVen, and David G. Russell. “Immune Activation of the Host Cell Induces Drug Tolerance in Mycobacterium tuberculosis Both in Vitro and in Vivo.” Journal of Experimental Medicine 213, no. 5 (2016): 809-825.
VanderVen, Brian C., Ruth J. Fahey, Wonsik Lee, Yancheng Liu, Robert B. Abramovitch, Christine Memmott, Adam M. Crowe, Lindsay D. Eltis, Emanuele Perola, David D. Deininger, Tiansheng Wang, Christopher P. Locher, and David G. Russell. “Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment.” PLOS Pathogens 11, no. 2 (2015).
Cornell Research Website Article
Pursuing a Cure—TB's Unsolved Mysteries