Cornell Research Cornell.edu

Expertise

Systems biology; functional genomics; epitranscriptome; epigenome; transcriptome; metagenome

Current Research Interest

New biochemical and computational methods in functional genomics; novel techniques in next-generation sequencing; algorithms for tumor evolution, genome evolution, DNA and RNA modifications; algorithms for genome/epigenome engineering; international standards for clinical-quality genome measurements/editing; integrated molecular portraits of genomes, epigenomes, transcriptomes, and metagenomes for NASA astronauts to establish the molecular foundations and genetic defenses for enabling long-term human space travel

Distinction

National Institutes of Health Transformative R01 Award
National Aeronautics and Space Administration Group Achievement Award
Pershing Square Sohn Cancer Research Alliance Young Investigator Award
Hirschl-Weill-Caulier Career Scientist Award
Vallee Foundation and WorldQuant Foundation Scholar Award
Center for Disease Control and Prevention Honor Award for Standardization of Clinical Testing

Selected Publications

Garrett-Bakelman, Francine E., Manjula Darshi, Stefan J. Green, Ruben C. Gur, Ling Lin, and Brandon R. Marcias, et al. “The NASA Twins Study: A Multidimensional Analysis of a Year-Long Human Spaceflight.” Science 365, no. 6436 (2019).

Li, Sheng, Francine E. Garrett-Bakelman, Stephen S. Chung, Mathijs A. Sanders, Todd Hricik, Franck Rapaport, and Jay Patel, et al. “Distinct Evolution and Dynamics of Epigenetic and Genetic Heterogeneity in Acute Myeloid Leukemia.” Nature Medicine 22, no. 7 (2016): 792-799.

Cornell Research Article

Strengthening the Human Genome