Carl F. Nathan

R.A. Rees Pritchett Professor and Chairman
Microbiology and Immunology, Weill Cornell Medicine

Contact Information

413 East 69th Street #1124
Weill Cornell Medicine
New York, NY 10021
p: (212) 746-6505

Carl F. Nathan

R.A. Rees Pritchett Professor and Chairman
Microbiology and Immunology, Weill Cornell Medicine

Expertise
Innate immunity; inflammation; macrophages; neutrophils; nitric oxide; tuberculosis; antimicrobial agents

Current Research Interest
Host-pathogen interactions, focusing on macrophages and Mycobacterium tuberculosis (Mtb); host pathways controlling susceptibility and resistance to Mtb; biology of Mtb in non-replicating (NR) states; approaches to overcome the phenotypic resistance of non-replicating Mtb to most antibiotics by developing new kinds of antimicrobial molecules

Distinction
National Academy of Sciences
National Academy of Medicine
American Academy of Arts and Sciences
Robert Koch Prize
Anthony Cerami Prize in Translational Medicine
Milstein Award of the International Cytokine & Interferon Society

Selected Publications
Vaubourgeix, Julian, Gang Lin, Neeraj Dhar, Nicolas Chenouard, Xiuju Jiang, Helene Botella, Tania Lupoli, Olivia Mariani, Guangli Yang, Ouathek Ouerfelli, Michael Unser, Dirk Schnappinger, John McKinney, and Carl Nathan. “Asymmetric Distribution of Irreversibly Oxidized, ClpB-associated Proteins in Stressed Mycobacteria.” Cell Host and Microbe 117 (2015): 179-190.

Nathan, Carl. “Bacterial Pathogenesis: Fresh Approaches to Anti-infective Therapies.” Science Translational Medicine 4 (2012): 1-13.

Cornell Research Website Article
The Immune System and Infectious Disease