Carl F. Nathan
Innate immunity; inflammation; macrophages; neutrophils; nitric oxide; tuberculosis; antimicrobial agents
Current Research Interest
Host-pathogen interactions, focusing on macrophages and Mycobacterium tuberculosis (Mtb); host pathways controlling susceptibility and resistance to Mtb; biology of Mtb in non-replicating (NR) states; approaches to overcome the phenotypic resistance of non-replicating Mtb to most antibiotics by developing new kinds of antimicrobial molecules
National Academy of Sciences
National Academy of Medicine
American Academy of Arts and Sciences
Robert Koch Prize
Anthony Cerami Prize in Translational Medicine
Milstein Award of the International Cytokine & Interferon Society
Vaubourgeix, Julian, Gang Lin, Neeraj Dhar, Nicolas Chenouard, Xiuju Jiang, Helene Botella, Tania Lupoli, Olivia Mariani, Guangli Yang, Ouathek Ouerfelli, Michael Unser, Dirk Schnappinger, John McKinney, and Carl Nathan. “Asymmetric Distribution of Irreversibly Oxidized, ClpB-associated Proteins in Stressed Mycobacteria.” Cell Host and Microbe 117 (2015): 179-190.
Nathan, Carl. “Bacterial Pathogenesis: Fresh Approaches to Anti-infective Therapies.” Science Translational Medicine 4 (2012): 1-13.