B. Franklin Pugh

Professor
Molecular Biology and Genetics, College of Arts and Sciences/Physiology and Biophysics, Weill Cornell Medicine

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Provided

Contact Information

465 Biotechnology Building
Cornell University
Ithaca, NY 14853
p: (607) 255-4954

B. Franklin Pugh

Professor
Molecular Biology and Genetics, College of Arts and Sciences/Physiology and Biophysics, Weill Cornell Medicine

Expertise

Genome biology; DNA transcription; biochemistry of protein-DNA interactions

Current Research Interest

Transcription pre-initiation complex assembly at inducible and constitutive promoters; impact of environmental stress on transcription stalling; how protein-DNA architecture controls chromosomes; development of epigenomic experimental and analysis tools

Distinction

American Association for the Advancement of Science Fellow
Pennsylvania State University Faculty Scholars Medal
Pennsylvania State University Evan Pugh University Professor
Pennsylvania State University Willaman Professorship in Molecular Biology
Greater Philadelphia Area Professorship

Selected Publications

Badjatia, Nitika, Matthew J. Rossi, Alain R. Bataille, Chitvan Mittal, William K. M. Lai, and B. Franklin Pugh. “Acute Stress Drives Global Repression through Two Independent RNA Polymerase II Stalling Events in Saccharomyces.” Cell Report 34, no. 3 (2021):108640.

Rossi, Matthew J., Prashant K. Kuntala, William K. M. Lai, Naomi Yamada, Nitika Badjatia, Chitvan Mittal, Guray Kuzu, Kylie Bocklund, Nina P. Farrell, Thomas R. Blanda, Joshua D. Mairose, Ann V. Basting, Katelyn S. Mistretta, David J. Rocco, Emily S. Perkinson, Gretta D. Kellogg, Shaun Mahony, and B. Franklin Pugh. “A High-Resolution Protein Architecture of the Budding Yeast Genome.” Nature (March 10, 2021).

Cornell Research Website Article

The Vast Machineries of Gene Regulation