Ari M. Melnick

Gebroe Family Professor of Hematology/Oncology; Director, Sackler Center for Biomedical and Physical Sciences
Gebroe Family Professor of Hematology/Oncology, Weill Cornell Medicine

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Ari M. Melnick
Patricia Kuharic

Contact Information

BB-1462 413 East 69th Street
Weill Cornell Medicine
New York, NY 10021
p: (646) 962-6725

Ari M. Melnick

Gebroe Family Professor of Hematology/Oncology; Director, Sackler Center for Biomedical and Physical Sciences
Gebroe Family Professor of Hematology/Oncology, Weill Cornell Medicine

Expertise

Biology of the immune system; lymphomas and leukemias; epigenetics; cancer experimental therapeutics

Current Research Interest

Mechanisms through which the epigenome programs the normal immune response; how mutations in epigenetic modifier genes causes lymphoma; the molecular epigenetic blueprints that determine the biology of acute leukemias; novel therapeutic agents and regimens for patients with lymphomas and leukemias

Distinction

Sidney Kimmel Foundation Scholar in Cancer Research
Leukemia and Lymphoma Society Scholar
American Society of Hematology Scholar Award
Burroughs Wellcome Fund Clinical Scientist Award in Translational Research
American Society of Clinical Investigation
Association of American Physicians

Selected Publications

Duy Cihangir, Matt Teater, Francine E. Garrett-Bakelman, Tak C. Lee, Cem Meydan, Jacob L. Glass, Meng Li, et al.”Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.” Cancer Discovery (2019).

Hatzi, Katerina, Huimin Geng, Ashley S. Doane, Cem Meydan, Reed LaRiviere, Mariano Cardenas, Cihangir Duy, et al. “Histone Demethylase LSD1 is Required for Germinal Center Formation and BCL6-Driven Lymphomagenesis.” Nature Immunology 20 (2019): 86-96.

Cornell Research Website Article

Figuring out How to Control Cancer