John T. Lis
John T. Lis
Gene regulation; transcription; chromatin structure; genomics; RNA aptamers
Current Research Interest
Develop genetic, optical, and biochemical approaches to study transcription regulation; understand chromatin and overall nuclear architecture in regulating the genome; develop RNA aptamers as drugs to inhibit macromolecular interactions in cells and to use specifically to elucidate mechanisms of gene regulation
American Academy of Arts and Sciences
National Academy of Sciences
Helen Hay Whitney Foundation Postdoctoral Fellowship
National Institutes of Health MERIT Award
John Simon Guggenheim Memorial Foundation Fellowship
Mahat, Dig B., Herbert H. Salamanca, Fabiana M. Duarte, Charles G. Danko, and John T. Lis. “Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation.” Molecular Cell 62, no. 1 (2016): 63-78.
Kwak, Hojoong, Nicholas J. Fuda, Leighton J. Core, and John T. Lis. “Precise Maps of RNA Polymerase Reveal How Promoters Direct Initiation and Pausing.” Science 339, no. 6122 (2013): 950-953.
Cornell Research Website Article
Tools for Observing Gene Transcription