Frederick R. Maxfield
Optical microscopy and biophysical techniques; digital imaging devices; confocal microscopes; multiphoton microscopy; automated microscopy systems; and image processing computers for analyzing processes that occur at specific sites within cells
Endocytic trafficking; kinetic models for endocytic membrane traffic of receptors, ligands, and membrane lipid components; disease-related endocytic processes
Pipalia, Nina, Kanagaraj Subramanian, Shu Mao, Harold Ralph, Darren M. Hutt, Samantha M. Scott, William E. Balch, and Frederick Maxfield. “Histone deacetylase inhibitors correct the cholesterol storage defect in most NPC1 mutant cells.” Journal of Lipid Research 58, no. 4 (2017): 695-708.
Haka, Abigail S., Valéria C. Barbosa-Lorenzi, Hyuek Jong Lee, Domenick J. Falcone, Clifford A. Hudis, Andrew J. Dannenberg, and Frederick R. Maxfield. “Exocytosis of Macrophage Lysosomes Leads to Digestion of Apoptotic Adipocytes and Foam Cell Formation.” Journal of Lipid Research 57, no.6 (2016): 980-992.v
Cornell Research Website Article
Clearing Out the Waste