Hening Lin

Professor
Chemistry and Chemical Biology, College of Arts and Sciences

Hening Lin-1119.jpg

Jesse Winter

Contact Information

287 Physical Sciences Building
Cornell University
Ithaca, NY 14853
p: (607) 255-4650

Hening Lin

Professor
Chemistry and Chemical Biology, College of Arts and Sciences

Expertise
Chemical biology; enzymology; biochemistry; enzyme inhibitors; signal transduction

Current Research Interest
Discovering and understanding novel protein modifications by studying orphan enzymes; developing enzyme inhibitors as therapeutic candidates for treating human diseases; using chemical technology to understand cellular signal transduction pathways

Distinction
Howard Hughes Medical Institute Investigator
Pfizer Award in Enzyme Chemistry

Selected Publications
Jing, Hui, Jing Hu, Bin He, Yashira L. Negrón Abril, Jack Stupinski, Keren Weiser, Marisa Carbonaro, Ying-Ling Chiang, Teresa Southard, Paraskevi Giannakakou, Robert S. Weiss, and Hening Lin. “A SIRT2-Specific Inhibitor Promotes c-Myc Oncoprotein Degradation and Inhibits Tumor Growth.” Cancer Cell 29 (2016): 297–310.

Jiang, Hong, Saba Khan, Yi Wang, Guillaume Charron, Bin He, Carlos Sebastian, Jintang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao, and Hening Lin. "Sirt6 Regulates TNF-alpha Secretion through Hydrolysis of Long-Chain Fatty Acyl Lysine." Nature 496 (2013).

Cornell Research Website Article
Seven Sirtuins and Anticancer Activities