Genetics; biochemistry; molecular biology
Current Research Interest
Mismatch repair; DNA replication and recombination; meiotic crossing over; hereditary form of colon cancer
Carpenter Award Winner, Cornell University
Kim, Yoori, Christopher M. Furman, Carol M. Manhart, Eric Alani, and Ilya J. Finkelstein. “Intrinsically Disordered Regions Regulate both Catalytic and Non-Catalytic Activities of the MutLα Mismatch Repair Complex.” Nucleic Acids Research 47, no. 4 (2019): 1823-1835.
Manhart, Carol M., Xiaodan Ni, Martin A. White, Joaquin Ortega, Jennifer A. Surtees, and Eric Alani. “The Mismatch Repair and Meiotic Recombination Endonuclease Mlh1-Mlh3 is Activated by Polymer Formation and can Cleave DNA Substrates in Trans.” PLoS Biology 15 (2017): e2001164.