Siu Sylvia Lee
Molecular genetics; genomics; Caenorhabditis elegans; aging; longevity; transcription factors; chromatin regulation
Current Research Interest
Molecular genetic and genomic dissections of aging and age-dependent degenerations; roles of major transcriptional and chromatin regulators; germline stem cells; and mitochondrial signaling in longevity and neurodegeneration of Caenorhabditis elegans
The Ellison Medical Foundation New Scholar in Aging
The Ellison Medical Foundation Senior Scholar in Aging
Glenn Foundation for Medical Research Award for Research in Biological Mechanisms of Aging
Chang, Hsin-Wen, Steve Pisano, Amaresh Chaturbedi, Jennifer Chen, Sarah Gordon, Aiswarya Baruah, and Siu Sylvia Lee. “Transcription Factors CEP-1/p53 and CEH-23 Collaborate with AAK-2/AMPK to Modulate Longevity in Caenorhabditis elegans.” Aging Cell 16, no. 4 (2017): 814-824.
Pu, Mintie, Zhuoyu Ni, Minghui Wang, Xiujuan Wang, Jason G. Wood, Stephen L. Helfand, Haiyuan Yu, and Siu Sylvia Lee. “Trimethylation of Lys36 on H3 Restricts Gene Expression Change During Aging and Impacts Life Span.” Genes & Development 29, no. 7 (2015): 718-731.